Our Research
Transforming immunotherapy, from bench to bedside.
The Ruella Lab at the University of Pennsylvania develops next-generation immunotherapies to treat lymphoid malignancies and autoimmune diseases. Our research bridges basic science, translational discovery, and clinical trials. By biobanking patient samples, we uncover mechanisms of resistance and toxicity—and use this knowledge to design smarter, more effective treatments. Our mission is simple: translate scientific discovery into real cures for patients.
Our Research
Transforming immunotherapy, from bench to bedside.
The Ruella Lab at the University of Pennsylvania develops next-generation immunotherapies to treat lymphoid malignancies and autoimmune diseases. Our research bridges basic science, translational discovery, and clinical trials. By biobanking patient samples, we uncover mechanisms of resistance and toxicity—and use this knowledge to design smarter, more effective treatments. Our mission is simple: translate scientific discovery into real cures for patients.
Our Research
Transforming immunotherapy, from bench to bedside.
The Ruella Lab at the University of Pennsylvania develops next-generation immunotherapies to treat lymphoid malignancies and autoimmune diseases. Our research bridges basic science, translational discovery, and clinical trials. By biobanking patient samples, we uncover mechanisms of resistance and toxicity—and use this knowledge to design smarter, more effective treatments. Our mission is simple: translate scientific discovery into real cures for patients.
Principal Investigator
Marco Ruella, MD, is Assistant Professor of Medicine in the Division of Hematology/Oncology and the Center for Cellular Immunotherapies and Scientific Director of the Lymphoma Program at the Hospital of the University of Pennsylvania.
Principal Investigator
Marco Ruella, MD, is Assistant Professor of Medicine in the Division of Hematology/Oncology and the Center for Cellular Immunotherapies and Scientific Director of the Lymphoma Program at the Hospital of the University of Pennsylvania.
Principal Investigator
Marco Ruella, MD, is Assistant Professor of Medicine in the Division of Hematology/Oncology and the Center for Cellular Immunotherapies and Scientific Director of the Lymphoma Program at the Hospital of the University of Pennsylvania.
Our Team
Patrizia Porazzi, PhD
Jean Lemoine, MD
Federico Stella, MD
Martina Pucillo, MD
Siena Nason
Ziyu Li, MS
Vrutti Patel, MS
Melody Tan
Audrey Bochi-Layec
Anushka Anant Padmanabhan, MS
Puneeth Guruprasad, PhD
Pedram Bayat
Luca Paruzzo, MD
Alberto Carturan, MD
Ivan Cohen, PhD
Ranjani Ramasubramanian
Linhui Chen, MS
Rebecca Yelton
Antonio Imparato, MD
Alessandra Azure
Shan Liu, PhD
Open Positions
We are seeking post-doctoral fellows to study the mechanisms of relapse after Chimeric Antigen Receptor T Cell immunotherapy and develop novel CART therapies.
Open Positions
We are seeking post-doctoral fellows to study the mechanisms of relapse after Chimeric Antigen Receptor T Cell immunotherapy and develop novel CART therapies.
Open Positions
We are seeking post-doctoral fellows to study the mechanisms of relapse after Chimeric Antigen Receptor T Cell immunotherapy and develop novel CART therapies.
Support us
If you would like to make a monetary contribution, please see the link below.
Thank you in advance for your support!
Select "Special Reason" and leave a note: “Donation to fund Dr. Marco Ruella’s research."
Support us
If you would like to make a monetary contribution, please see the link below.
Thank you in advance for your support!
Select "Special Reason" and leave a note: “Donation to fund Dr. Marco Ruella’s research."
Support Us
If you would like to make a monetary contribution, please see the link below. Thank you in advance for your support! Select "Special Reason" and leave a note: “Donation to fund Dr. Marco Ruella’s research."
Support Us
If you would like to make a monetary contribution, please see the link below. Thank you in advance for your support! Select "Special Reason" and leave a note: “Donation to fund Dr. Marco Ruella’s research."
Perelman Center for Advance Medicine
3400 Civic Center Boulevard
South Tower, 8th Floor, Bay 321
Philadelphia, PA 19104
© The Trustees of the University of Pennsylvania
Perelman Center for Advance Medicine
3400 Civic Center Boulevard
South Tower, 8th Floor, Bay 321
Philadelphia, PA 19104
© The Trustees of the University of Pennsylvania
Perelman Center for Advance Medicine
3400 Civic Center Boulevard
South Tower, 8th Floor, Bay 321
Philadelphia, PA 19104
© The Trustees of the University of Pennsylvania
Perelman Center for Advance Medicine
3400 Civic Center Boulevard
South Tower, 8th Floor, Bay 321
Philadelphia, PA 19104
© The Trustees of the University of Pennsylvania